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Traumatic brain injury

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Traumatic brain injury¹
Classification & external resources
ICD-10 S06
ICD-9 800.0-801.9, 803.0-804.9, 850.0-854.1

Traumatic brain injury (TBI), traumatic injuries to the brain, also called intracranial injury, or simply head injury, occurs when a sudden trauma causes brain damage. TBI can result from a closed head injury or a penetrating head injury and is one of two subsets of acquired brain injury (ABI). The other subset is non-traumatic brain injury (i.e. stroke, meningitis, anoxia). Parts of the brain that can be damaged include the cerebral hemispheres, cerebellum, and brain stem (see brain damage). Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. Outcome can be anything from complete recovery to permanent disability or death. A coma can also affect a child's brain.

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Approximately 90% of the overall budget of NINDS is used to fund extramural research. This section of the website describes the current NINDS funding strategy, the mechanisms NINDS uses to support extramural research, its areas of research interest and its policies.

  • Funding Strategy
    Each year, NINDS establishes a set of funding plans based on the appropriations received from Congress... [more]

  • Funding Opportunities
    Unsolicited, investigator-initiated applications in areas of research interest are accepted on standard Receipt Deadlines. Applicant forms are available online.
  • In addition, NINDS also periodically solicits applications and proposals on specific topics. A list of current solicitations (RFAs, PAs, Notices and RFPs) is found in this section... [more]

  • Grant Mechanisms (including research grants and cooperative agreements)
    • A description of the mechanisms NINDS uses to support research... [more]
    • Helpful information regarding Grants Policies... [more]
    • Information on the status of a grantee or applicant's grant/application: NIH eRA Commons allows a Principal Investigator to review the current status of all their grant applications and review detailed information associated with the grant... [more]
    • Answers to Frequently Asked Questions about NINDS Funding... [more]

  • Contract Mechanisms
    Research and development contracts are awarded for specific scientific inquiry directed towards particular areas identified as needs by the Government. The Contracts Management Branch provides more information on this topic... [more]

  • Clinical Research
    Research that involves human subjects is governed by a number of additional policy and oversight requirements. NINDS requires the clinical research it funds to meet high standards of scientific rigor in study design and execution as well as vigilance in the protection of human subjects... [more]




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